In William Goldman’s (may he rest in piece) great book, Adventures in the ScreenTrade, he makes the most true statement ever:
No one knows what works.
He was talking about movies, but it’s true for any story. Twilight made the author rich (why? Who knows?). 50 Shades of Grey, a bad story about bad bondage IN THIS DAY IN AGE, was phenomenally successful. Why?
In the movie trade, thousands of things can go wrong that makes a bad script good or a good script bad.
You may have a crazy concept. You may think it isn’t salable, but if 50 Shades of Grey can be successful in the Me Too era, there isn’t any crazy idea that can work.
When you begin writing, don’t think about “is it publishable?” Think instead, “how do I make this crazy idea work?”
If you need permission to write that wacky concept, consider it given. Get writing.